?codon

codon發(fā)音

英：['k??d?n]　　美：['ko?d?n]

英：　　美：

codon中文意思翻譯

n. [生物]遺傳密碼子

codon常見(jiàn)例句

1 、Keywords pseudorabies virus （PRV）;G+C content;relative synonymous codon usage RSCU;bias;regulatory gene;───偽狂犬病病毒;G+C含量;同義密碼子相對使用度（RSCU）;偏差;調節基因;

2 、Site discrepancy of synonymous codon usage in SARS coronavirus and other viruses in Coronaviridae───SARS及其他幾種冠狀病毒密碼子使用偏性的位點(diǎn)差異

3 、Moreover, species with near homology relationship on evolution share the near codon usage frequency and preference index or the similar index.───在同源性方面，在進(jìn)化上比較接近的物種，基因的密碼子使用頻率和使用偏性指標比較接近或基本相同。

4 、RT PCR showed that all samples expressed HCP gene, only one missense mutation at codon 225 (AAC to AGC, Asn to Ser) within N terminal SH2 domain was found in an ALL patient.───RT PCR顯示所有標本中都有HCP基因表達 ,僅在 1例急性淋巴細胞性白血病細胞中發(fā)現一錯義突變 ,發(fā)生在HCP基因氨基末端的SH2結構域 ;

5 、Thus, codon usage bias of nuclear genes appeared to be affected by translational selection.───因此，核基因的密碼子使用偏好性受到翻譯選擇的影響。

6 、Keywords codon usage preference;vasostatin120 180;inclusion body;refolding strategy;chick embryo chorioallantoic membrane assay;───偏愛(ài)密碼子;血管內皮抑制素120-180;包涵體;變復性;雞胚尿囊膜試驗;

7 、They worked out the code and they worked out that it was arranged in threes a triplet code, with each group of three bases called a codon.─── 他們破譯了密碼 他們發(fā)現它是一種三聯(lián)體密碼 每三個(gè)堿基的組合形成一個(gè)密碼子

8 、A protein called a release factor binds directly to the stop codon, causing the addition of a water molecule instead of an amino acid to the polypeptide chain.───一種叫做釋放因子的蛋白質(zhì)直接結合在終止密碼子上，導致一個(gè)水分子而不是氨基酸被加在肽鏈末端。

9 、PTC124 is an orally administered small molecule that targets a type of disease-causing genetic error known as a nonsense mutation, or premature stop codon.───PTC124是一種口服式小分子化合物，它的標的是針對一些因為”無(wú)義”基因突變的疾病。

10 、Secondly, LN9912 EO gene was cloned into pGEX4T, pETSO and pMAL-p2X respectively, with strains BL21 and BL21 (DE3) codon plus, BL21(DE3) and BL21 (DE3) codon plus, TB1 and BL21 C DE3) codon plus as their corresponding expression hosts.───其次，將豬瘟兔化弱毒株(HCLV)EO基因分別**入pGEX4T，pET30，pMAL-p2X中，并分別構建了以BL21和BL21(DE3)codon plus,BL21(DE3)和BL21(DE3)codon plus,TB1和BL21(DE3)codon plus為宿主菌株的原核表達系。

11 、Furthermore, the earlier the species differentiation time on evolution, the lower the difference of the codon usage frequency and preference and the higher by contraries.───在進(jìn)化上分化時(shí)間越早的物種，密碼子使用頻率和使用偏性的差異較小，反之則較大；

12 、And you can see that we've got some punctuation in our sentences, because it turns out that there are special codons that make something like a full stop at the end of the protein.─── 如圖所示 句子中會(huì )有標點(diǎn)符號 因為在蛋白質(zhì)鏈的尾端 有一些特殊的密碼子起著(zhù)句號的作用

13 、The precore stop codon mutation was found in 7 AsCs and 10 CAH cases.───AsC與CAH組中，前C終28變異分別為7例和10例；

14 、Codon Optimization of Antibacterial Peptide Magainin and CecA-mil Gene and Over -expression in Pichia pastoris───Magainin和cecA-mil抗菌肽基因的密碼子優(yōu)化及在畢赤酵母中的高效表達

15 、synonymous codon repeat sequence───同義密碼子重復序列

16 、Furthermore, a fragment of 150bp from start codon ATG to 150nt showed the most variation.───從ATG至第150bp區段的核苷酸序列變異頻率最高。

17 、There is terminate codon TAA of the whole ORF at the 3D coding region termination.───在3D編碼區末端有整個(gè)ORF的終止密碼子TAA。

18 、Analyzing the Characteristics of Start Codon in Prokaryote and Yeast Genomes───原核生物和酵母基因組中起始密碼的特征分析

19 、SU-DHL-9 had homozygous deletion of p16 gene. Meanwhile, SU-DHL-1 and Daudi cell lines had mutation of the second exon of p16 gene. GAC in codon 30 mutated into AAC.───SU-DHL-9有p16基因的純合缺失,而SU-DHL-1和Daudi細胞系有p16基因的第二外顯子的突變,SU-DHL-1的測序結果為密碼子30的GAC突變?yōu)锳AC,密碼子35的GCT突變?yōu)锳CT,密碼子40與41之間**入了一個(gè)C;

20 、Bias of Base Composition and Codon Usage in Pseudorabies Virus Genes───偽狂犬病病毒基因編碼區堿基組成與密碼子使用偏差

21 、And it turns out that there's more to genes than just strings of codons.─── 他們發(fā)現基因并非 只是一串單純的密碼子

22 、Codon Optimization and Expression of Norovirus Capsid Proteins in Insect Cells───人諾如病毒衣殼蛋白的密碼子優(yōu)化及在昆蟲(chóng)細胞中的表達

23 、signal codon───信號密碼子

24 、Keywords melitten;alpha fetoprotein;adenoviruses;human;sequence homology;nucleic acid;codon;───關(guān)鍵詞蜂毒肽;甲胎蛋白類(lèi);腺病毒;人;序列同源性;核酸;密碼子;

25 、Study on the Codon Usage of Chinese Hamster Ovary Cells───中華倉鼠卵巢細胞密碼子的研究

26 、Correlation Between the Mutation of the DCC Gene Codon 201 and Gastric Cancer.───DCC基因201密碼子突變與胃癌相關(guān)性的研究

27 、A triplet of nucleotides; a codon.───三核苷酸，密碼子

28 、Each three-letter sequence of nucleotides (or codon) stands for a specific amino acid.GCA, for example, codes for alanine, one of the 20 different amino acids found in animal organisms.───其中每三個(gè)一組的核苷酸排序（稱(chēng)為密碼子）代表特定胺基酸，譬如GCA是丙胺酸的編碼，而丙胺酸只是動(dòng)物體內20種不同的胺基酸之一。

29 、The detection rates of pre-S2 start codon mutation were significantly different in different groups: from 50.00% (HCC), 39.47% (LC), 8.00% (CH), to ASC (0).───前S2起始碼變異在HCC、LC組的檢出率分別為50.00%、39.47%,明顯高于慢性肝炎組的8.00%、慢性無(wú)癥狀乙型肝炎表面抗原攜帶者組的0(P值均

30 、Among these 10 cases of CJD patients, 8 cases are codon 129 homozygous Met/Met and 2 cases are heterozygous Met/Val. No codon129 homozygous Val/Val was found.───10例CJD中 8例為12 9密碼子甲硫氨酸純合子型 ,2例 12 9密碼子甲硫氨酸和纈氨酸雜合型 ,無(wú) 12 9密碼子纈氨酸純合子型。

31 、And some base bias of the 1st and the 2nd site of a codon also are related to gene expression level as well.───發(fā)現密碼子的第1位點(diǎn)和第2位點(diǎn)的某些堿基分布與基因表達水平有關(guān)。

32 、coding for the same amino acid as another codon───為作為另一個(gè)密碼子的同樣的氨基酸編密碼的

33 、Methods and Applications of Inserting a Stop Codon into a Cloned Gene with PCR───利用PCR在已克隆基因末端添加終止密碼的方法與應用

34 、The total number of nucleotides between a stop codon of rbcL gene and a HindIII site in cemA gene were 2 808 and 2 810 bp in Ae.───從rbcL基因的終止密碼子到cemA基因內的HindIII位點(diǎn),Ae.

35 、Between codon 40 and 41, C was inserted. SU-DHL-4 and SU-DHL-6 had bcl-2/JH fusion genes. The significance of gene conformational changes affected pathogenesis, development of malignant lymphoma cell lines was discussed.───SU-DHL-4和SU-DHL-6有bcl-2/JH基因的重排,討論了基因結構的變化在惡性淋巴瘤細胞系發(fā)生發(fā)展中的意義。

36 、Keywords Tetrahydrofolate dehydrogenase;Cricetulus;Ovary;DNA;complementary;Codon;───四氫葉酸脫氫酶;倉鼠屬;卵巢;DNA;互補;密碼子;

37 、Keywords ACAT1,trans-splice,chromosome,start codon,translation,regulation;───反式剪接;染色體;翻譯起始密碼子;表達;調控;

38 、Correlation between Synonymous Codon Usage and the Amino Acid Sequence Contexts───同義密碼子用語(yǔ)與氨基酸序列上下文的關(guān)聯(lián)

39 、Mitochondria, the tiny power generators within all kinds of cells, have their own genomes, and many have also developed their own codon assignments.───再者，細胞內的迷你發(fā)電廠(chǎng)粒線(xiàn)體也有自己的基因組，而許多粒線(xiàn)體也發(fā)展出自己的密碼子對應系統。

40 、The detected ratios of pre-S2 start codon and pre-S deletion mutations were significantly higher in genotype C than in genotype B (43.04% vs 1.23%, 36.71% vs 19.75%, P < 0.05, respectively).───C基因型前S2起始碼變異的檢出率為43.04%,高于B型的1.23%(P

41 、Among 98 mutations, there is no insertion or deletion, and Yellow cattle and Yak have the same codon bias except the isoleucine codon.───共檢測到98個(gè)變異位點(diǎn),未發(fā)現**入和缺失,牦牛和黃牛除了異亮氨酸以外有著(zhù)相同的密碼子偏好.

42 、But researchers have also documented cases in which the use of an uncommon codon appears to slow protein manufacture in a way that maximizes efficient folding.───但是也有研究報告指出使用不常見(jiàn)的密碼子會(huì )減緩蛋白質(zhì)制造的速度，反而大幅增加了摺疊的效率。

43 、We found that first, the "Kozak rule" could be confirmed and extended efficiently. The bases in position -9 (nine nucleotides upstream from the ATG codon), -8, -6, -4, -3, -2, -1, +4, +5 and +6 were included in the rule.───在大量智人mRNA序列統計分析的基礎上，驗證了“Kozak規則”，并進(jìn)行了有效擴展，將-9，-8，-6，-4，-3，-2，-1、+4，+5，+6均納入新的規則之中。

44 、Coding for the same amino acid as another codon.───為作為另一個(gè)密碼子的同樣的氨基酸編密碼的.

45 、The initiation codon represents the first amino acid, N-formyl methionine, at the N terminus of the polypeptide.───即編碼多肽N-端第一個(gè)氨基酸即甲硫氨酸（N-甲酸化的）的密碼子。

46 、All the authors are also scientific advisers to Codon Devices in Cambridge, Mass., the first commercial enterprise launched to apply engineering principles to synthetic biology.───他們共同撰寫(xiě)這篇文章，是因為彼此專(zhuān)長(cháng)各異，對生物制程的發(fā)展有不同的貢獻，代表了生物工程學(xué)跨學(xué)科的特色。

47 、ambiguous codon───多義密碼子

48 、Comparatively, it is the species function rather than the gene function that determines their gene codon usage patterns.───與基因的功能對密碼子使用的影響相比，這些泉古菌密碼子的使用偏向性更是由其物種所決定的。

49 、Introduction :About 30% of inherited genetic disorders in humans result from premature termination codon mutations.───前言:約30%的人類(lèi)遺傳性疾病起源于過(guò)早出現的終止密碼子突變。

50 、All 13 protein coding genes (PCGs) of the G. gratiosa mitogenome start with a typical ATN codon.───優(yōu)雅蟈螽線(xiàn)粒體基因組的13 個(gè)蛋白質(zhì)編碼基因均以ATN作為起始密碼子；

51 、The Factors Shaping Synonymous Codon Usage in the Genome of Burkholderia mallei.───Sheng Zhao，Qin Zhang，Zhihua Chen，Yixin Zhao， Jincheng Zhong (通訊作者).

52 、Analysis of the secondary structure around the initiati on codon among three mRNAs showed that the secondary structure of the mRNA from parg-leuS was the strongest of the three mRNAs.───分析三種leuSmRNA在起始密碼子附近的二級結構 ,發(fā)現從 parg leuS轉錄的mRNA的二級結構最強。

53 、Result1 C-kit mutation in GIST: C-kit gene mutations were found in three of eight GIST samples. The first was an insertion of 12 bps at Codon 579;───1 C-kit基因突變檢測：8例GIST C-kit基因exon11測序結果顯示3例含突變：1例為**入性突變，白密碼子Codon 579**入12bp；

54 、codegenerate codon───互簡(jiǎn)并密碼子

55 、synonymous codon───同義密碼子

56 、Keywords Mannose-binding lectins;Polymerase chain reaction;Codon;Mutation;───關(guān)鍵詞甘露糖結合凝集素類(lèi);聚合酶鏈反應;密碼子;突變;

57 、Relations between synonymous codon usage and protein structure───同義密碼子用語(yǔ)與蛋白質(zhì)二級結構信息

58 、Frequencies of genetypes at codon 52 of MBL Exon I in healthy chinese Hans nationality───52位基因頻率調查

59 、a section within a strand of messenger RNA containing a codon altered through mutation so that it codes for a different amino acid───一個(gè)RNA螺旋體中包含的一個(gè)因突變而改變密碼子的部分，它能編碼成為另一種不同的氨基酸

60 、The high-frequency codons were selected by high-frequency codon analysis according to relative frequency of synonymous codon (RFSC) which is calculated by RFCS program written by ourselves.───利用自編的RFCS程序計算同義密碼子相對使用頻率(RFSC),并根據RFSC值篩選出高頻密碼子。

61 、With Kozak similar sequences of triple codon AAA:specifically enhancing the immunological results of Foot-and-Mouth disease DNA vaccine───含三聯(lián)密碼AAA的Kozak類(lèi)似序列特異性增強口蹄疫DNA疫苗的免疫效果

62 、The distance and the composition between the Shine-Dalgarno(SD)sequence and the start codon have, profound effect on the expression of prochymosin gene causing a 15fold difference.───Shine-Dalgarno序列與起始密碼子之間的距離與組成對凝乳酸原基因表達有明顯的影響,可導致其表達水平有15倍之差。

63 、Study on The Point Mutation at Codon 12 of H-ras Oncogene in Human Fetal Epithejial Cell Treated with ( Trans )-BPDE───反式-BPDE誘發(fā)人胎氣管上皮細胞H-ras癌基因點(diǎn)突變的研究

64 、Having more than one codon specify the same amino acid.Used of a genetic code.───兼并密碼子的有不止一個(gè)密碼子來(lái)指定同樣的氨基酸。

65 、The underlined nucleotides are the first upstream in-frame stop codon and the two putatie polyadenylation signals, respectiely.The asterisk indicates the stop codon.───加下劃線(xiàn)的核苷酸分別是這個(gè)讀碼框中上游的第一個(gè)終止密碼和兩個(gè)已經(jīng)認定的多核苷酸序列.星號標記的就是終止密碼.

66 、Keywords Human papillomavirus type 16 L1;recombinant adenovirus;recombinant baculovirus;expression;codon optimization;virus-like particle（VLP）;───人乳頭瘤病毒L1;16型;重組腺病毒;重組桿狀病毒;表達;密碼子優(yōu)化;病毒樣顆粒;

67 、Keywords 3 untranslated regions/genetics;Variation（genetics）;Hepacivirus/genetics;Codon;terminator;───3非翻譯區/遺傳學(xué);變異（遺傳學(xué)）;肝炎病毒/遺傳學(xué);密碼子;終止;

68 、K ras gene point mutation at codon 12 was found in human pancreatic carcinoma cell line PC 2, and the mutation style was CGT.───人胰腺癌細胞株P(guān)C 2存在K ras基因點(diǎn)突變 ,突變方式為CGT。

69 、Analysis of the relationship between codon frequency of prolactin gene and laying performance in five chicken breeds───五個(gè)雞群中催乳素基因密碼子使用頻率與產(chǎn)蛋量的關(guān)系分析

70 、Comparison and Analysis of Synonymous Codon Repeat Sequences in Different Genomes───不同基因組中同義密碼子重復序列的分析與比較

71 、relative synonymous codon usage───同義密碼子相對使用

72 、One codon had been deciphered, and the triplet UUU became the first word in the chemical dictionary of life.───于是頭一個(gè)密碼解開(kāi)了，UUU這三個(gè)核苷酸組成了生化字典里的第一個(gè)字。

73 、The Contrast Study of Base's Conservative Character and Correlative Character between E.coli and Yeast Gene for Adjacent Sequence of Initiation Codon or Termination Codon───E.coli和Yeast基因起始與終止密碼子鄰近序列堿基保守性、關(guān)聯(lián)性的對比研究

74 、Comparative Study on Mutations at Codon 12 of Ki-ras Gene Between Chinese and Western Patients with Pancreatic Cancer───中國人與西方人胰腺癌組織中Ki-ras基因第12密碼子突變表型的比較

75 、The style of K-ras gene point mutation at codon 12 was GAT in human pancreatic cancer cell line.───人胰腺癌細胞株P(guān)ANC-1存在K-ras基因的點(diǎn)突變,其突變方式為CAT。

76 、multi-mutants of YIDD and codon 528. 91% codon of YMDD mutants were GTG, ATX;───YIDD、528位點(diǎn)同時(shí)突變。 YMDD突變密碼子91%為:GTG、ATT;

77 、As gene type and function is fixed, species difference can also affect codon usage bias.The closer the consanguinity between species in evolution, the similar their codon usage bias is.───在基因的類(lèi)型和功能一定的情況下，物種的差異也會(huì )影響到密碼子的使用偏性，在進(jìn)化上親緣關(guān)系較近的物種間，其相對密碼子使用概率也較接近。

78 、Here's a codon of three bases and that will give us an amino acid, which we give another single letter code to.─── 這是三個(gè)堿基組成的一個(gè)密碼子 它代表一種氨基酸 我們給它一個(gè)單字母代碼

79 、Prion protein codon 129 genotype preva-lence is altered in primary progressive aphasia───原發(fā)進(jìn)行性失語(yǔ)患者的朊蛋白密碼子129基因型患病率改變

80 、Keywords p53 codon 72;polymorphism;homozygote;heterozygote;HPV-associated cervical cancer;───多態(tài)性;純合子;雜合子;HPV有關(guān)的宮頸癌;

81 、In human cDNA sequencing projecs, it is vital to know whether the first ATG codon is a real start codon or an in frame Met codon without initiation function.───在人類(lèi)cDNA序列確定全長(cháng)基因的過(guò)程中 ,必須判斷第一個(gè)ATG密碼子是真正的起始密碼子還是框內的非起始作用的甲硫氨酸密碼子 .

82 、A deletion of adenosine (A), at -241 (relative to initiation codon ATG), designated as Del(A) allele, was found in Laiwu compared with Yorkshire (GenBank accession number DQ463321-22).───克隆了豬DGAT1 5’調控區的部分序列(737 bp),在-241bp(相對于起始密碼子ATG)發(fā)現一處由單個(gè)腺嘌呤(A)缺失產(chǎn)生的新SNP位點(diǎn)(定義為等位基因Del(A) ) (GenBank收錄號:DQ463321-22);

83 、For example, the use of speciesspecific codon optimization results in increased protein production on a per-cell basis, leading to enhanced T-cell responses and antibody induction.───例如，使用物種特異性密碼子將會(huì )使每細胞單位的蛋白質(zhì)產(chǎn)量增加，從而加強T細胞的反應和抗體的吸附。

84 、multiple codon recognition───多密碼子識別, 多種密碼子識別

反密碼子的簡(jiǎn)并性？

分子生物學(xué)中，同一種氨基酸具有兩個(gè)或更多個(gè)密碼子的現象稱(chēng)為密碼子的簡(jiǎn)并性（degeneracy）。

對應于同一種氨基酸的不同密碼子稱(chēng)為同義密碼子（synonymous codon），只有色氨酸與甲硫氨酸僅有1個(gè)密碼子。

同義密碼子通常只在第3位堿基上不同，這樣可減少有害突變。

反密碼子的簡(jiǎn)并性？

簡(jiǎn)并性:同一個(gè)氨基酸有兩個(gè)或更多個(gè)密碼子對應的現象。

擺動(dòng)性:tRNA上的反密碼子與mRNA上的密碼子配對時(shí)，第一，第二位堿基嚴格配對，而第三位堿基配對不是很?chē)栏竦默F象。