?ligand

ligand發(fā)音

英：['l?g?nd]　　美：['l?g?nd]

英：　　美：

ligand中文意思翻譯

n. 配合基；向心配合價(jià)體

ligand常見(jiàn)例句

1 、The factors of influencing coordinate polymer structure, such as metal ions and ligand, were discussed. The reaction conditions of coordinate polymer were studied.───摘要討論了影響配合物結構的一些因素；金屬離子和配體等。也研究了配位聚合物的反應條件。

2 、The FT|Raman spectrum of 4,5|diaza|9|(4,5|ethylenedithio|1,3|dithiol|2|ylidene)|fluorene(DEDYF),a sulfur|rich conjugation ligand with chelating nitrogen,was studied.───文獻名稱(chēng)4,5-二氮-9-[4,5-雙(亞乙基硫代)-1,3-二硫雜環(huán)戊二烯-2-內翁鹽]-芴(DEDYF)的傅里葉-拉曼光譜研究

3 、Abstract The NGR peptide is a ligand specifically binding to tumor angiogenic blood vessels, and thus has potential usage in the diagnosis and therapy of tumor.───摘要 天門(mén)冬酰胺酰甘氨酰精氨酸(NGR)是特異性地**于腫瘤新生血管受體的多肽基序,在腫瘤診斷和治療方面具有潛在的應用前景。

4 、SAA ligand Lg could catalyze asymmetric addition of phenylacetylene to unactivated aromatic ketones in high yields (up to 83%) and high enantioslectivities (up to 83%ee).───SAA配體Lg用于催化炔基鋅對未活化酮的不對稱(chēng)加成反應,對于芳香酮的催化反應,收率可達83%,對映體選擇性可達83%ee。

5 、In five patient/donor pairs with AML-M_4 and AML-M_5,6 up-regulated (STAT5B,ligand p62 for the Lck SH2,CST3, LTC4S,myeloid leukemia factor 2 and epb72) and 1 down-regulated genes (CCR5) were identified.───5例AML M4和AML M5患者中亦存在 7條顯著(zhù)差異表達基因 ,其中上調表達 6條 (STAT5B ,ligandp6 2fortheLckSH2 ,CST3,LTC4S ,myeloidleukemiafactor 2 ,epb72 ) ,下調表達 1條 (CCR5 )。

6 、CD40-CD40 ligand interaction induced a robust stimulation of the DAG-PKC pathway and calcium mobilization from intracellular pool in PBMC.───CD40-CD40L相互作用能激活人外周血單核細胞[Ca~(2+)]_i動(dòng)態(tài)變化及二?；视?蛋白激酶C信號通路。

7 、The formation characteristics and conditionsof micellar mixed ligand complexes are also reported.───介紹了膠束混配絡(luò )合物的反應特點(diǎn)和形成條件。

8 、Radiolabelled glucose,amino acid and ligand are commonly used as PET tracer in meningioma diagnosis.───PET在腦膜瘤診斷中常用糖類(lèi)、氨基酸等代謝物類(lèi)顯像劑以及受體類(lèi)顯像劑。

9 、When the complex of anhydrous zinc acetate with 1,5-naphthalene diamine was formed, the anhydrous zinc acetate changed from a bidentate ligand to a unidentate ligand.───在無(wú)水乙酸鋅與1,5-萘二胺形成配位絡(luò )合物的過(guò)程中，無(wú)水乙酸鋅的結構從雙齒型轉變成單齒型。

10 、The measuring method of the coordination number and the researching achievements of coordination structure on metal complexes with organic ligand,especially for polymer compound,are reviewed.───介紹金屬離子與有機化合物特別是有機高分子化合物的配位數測定方法和配位結構的主要研究成果。

11 、It is also noticed PD-1 ligand, PD-L1 expression is abundant on many cancers.───PD-1配體(PD-L1)在許多癌組織中表達豐富，因此，負性共刺激分子對于調控免疫反應是非常重要的。

12 、The effects of the ligand structures on the enantioselectivity were also studied.───同時(shí)研究了配體的結構對反應的對映選擇性的影響。

13 、"Any ligand that can Bind to the metal at two or more points to form a ring structure, more stable than a nonchelated compound of the same general chemical formula, is a chelating agent.───任何一個(gè)配位體可以在兩個(gè)或兩個(gè)以上的點(diǎn)上與金屬連結,形成一個(gè)環(huán)狀結構,它比擁有同樣化學(xué)式的無(wú)螯合的化合物穩定,是一種螯合劑。

14 、Its ligand is sialyl Louis oligosaccharides or similar molecular structure,and expresses in neutrophils,eosinophils and normal bone marrow precursor cells.───其配體是唾液酸化的路易斯寡糖或類(lèi)似結構的分子,在中性粒細胞、嗜酸性粒細胞和正常骨髓前體細胞上大量表達。

15 、AAS and EA gave the results that the concentration of CuCl_2 and ligand were 1.67mmol/gcat, 1.54mmol/gcat respectively.───原子吸收以及元素分析結果表明,該負載催化劑上CuCl_2含量為1.67mmol/g,配體含量1.54mmol/g,兩者以接近1:1 的比例配位;

16 、Methods Expressions of Fas and Fas ligand(FasL) were detected in 30 lesions of discoid lupus erythematosus(DLE) and 5 skin specimens from healthy controls by immunohistochemical staining.───方法 采用免疫組化法檢測了 30例盤(pán)狀** (DL E)患者皮損及 5例正常對照皮膚 Fas及 Fas配體 (Fas L )的表達。

17 、This problem may be conveniently resolved by placing an "arm" between the matrix and ligand.───在載體與配基之間接上一只“手臂”，這個(gè)問(wèn)題就容易解決了。

18 、Among those factors, organic ligand was the most important matter influencing the morphology of DMC complex.───其中有機配體對DMC催化劑形態(tài)的影響是最主要的。

19 、Most of proteins firstly combine with ligand or form protein complex with other proteins, and then participate in the process of cell metabolism.───其中，多數蛋白質(zhì)是通過(guò)與配體結合或是作為蛋白質(zhì)復合物中的一部分參與細胞的代謝過(guò)程。

20 、Molecu lar docking serves as a method to simulate the interactions of two molecu les (such as ligand and receptor) and to predict their binding mode a nd affinity.───分子對接是研究分子間(如配體和受體)相互作用,并預測其結合模式和親合力的一種理論模擬方法。

21 、The departing halide extracts a proton from the second water and the generated hydroxyl ligand reacts with the ethylene, while remaining in the coordination sphere of the metal.───分開(kāi)的鹵化物從第二個(gè)水分子得到一個(gè)質(zhì)子，同時(shí)產(chǎn)生的羥基配合體與乙烯反應，留在了金屬的配位區內。

22 、Agmatine is a novel neurotransmitter and/or neuromodulator, which is the endogenic ligand of the imidazoline receptors.───摘要胍丁胺是一種新的神經(jīng)遞質(zhì)和／或神經(jīng)調質(zhì)，是咪唑啉受體的內源性配體。

23 、Because the binding of the neurotransmitter (ligand) to the receptor activates these ion channels, they are called ligand-gated channels to distinguish them from voltage-gated channels.───因為神經(jīng)遞質(zhì)和受體結合(配位)啟動(dòng)了這些離子通道,所以他們被稱(chēng)為配位門(mén)通道,以區別于電壓門(mén)通道。

24 、The ligand can carry a variety of functionalities, including fluorescent labels, affinity handles and attachments to a solid phase.───可使活細胞或固定細胞成像：配基可通過(guò)細胞膜，且共價(jià)鍵穩定，允許對活細胞或固定細胞成像。

25 、Fas and its ligand could play a an role in the injury of human glomerular cell.───Fas?FasL系統在Mcs凋亡中起著(zhù)重要作用。

26 、Two different methods for recycling ligand were tried in AD and AA reactions, respectively.───并采用兩種不同的方法進(jìn)行AD和AA反應中配體的回收和重復使用。

27 、Nociceptin/orphanin FQ (N/OFQ) is the endogenous ligand of the opioid receptor-like 1 receptor (NOP), the G-protein coupled receptor which shows overall 60% homology with the classical opioid receptors.───孤啡肽(Nociceptin/Orphanin FQ,N/OFQ)是阿片受體樣受體(Nociceptin/orphanin FQ receptor,NOP receptor)的內源性配基。

28 、Human CD21/CR2 is also the receptor for the EB viral membrane glycoprotein gp350/gp220 and HIV-1. CD21/CR2 shows various biological characteristics when it binds to ligand with its distinct domains.───同時(shí)人CD21/CR2也是EB病毒膜表面糖蛋白gp350/gp220、HIV-1等的受體,CD21/CR2以不同的結構域與這些配體結合,表現出多種生物學(xué)特性。

29 、The effect of organic ligand acidity and the amount of the catalyst on the oxidation reaction was investigated.───本文討論了配位體種類(lèi)及催化劑用量對反應的影響。

30 、When we used ligand 4a in the asymmetric addition of phenylacetylene to aldehydes at room temperature, the highest ee was up to 99%.───當我們用配體4a作為催化劑在對苯乙炔對醛的不對稱(chēng)加成反應中,最高的ee可達99%。

31 、Previous studies showed agmatine, an endogenous I1-imidazoline receptor ligand, prevents morphine dependence, but the mechanism remains unclear.───盡管以前研究表明胍丁胺能夠抑制嗎啡依賴(lài)，但其作用機制尚不明確。

32 、Asymmetric allylation of 2-nitrocycloketones was catalyzed by palladium with chiral ferrocenylphosphine ligand modified by monoaza crown ethers (A-D).───在用氮雜冠醚改良的手性二茂鐵膦與鈀的絡(luò )合物催化下,2-硝基環(huán)酮可進(jìn)行不對稱(chēng)烯丙基化反應。

33 、Affinity chromatography of MBP fusion protein relied on thebinding of ligand and ligand body, which were not affected by the concentration of MgSO4.───MBP融合蛋白的親和層析依賴(lài)于配體與配基的結合，不受溶液中離子濃度的影響；

34 、Instant ligand libraries beat the time-to-market constraint.───實(shí)時(shí)配位體庫打破了時(shí)間的市場(chǎng)局限。

35 、FCM can display soundly the characteristic of the receptor ligand combination between ASGPR and FITC NGA.───FCM能夠良好地揭示FITC NGA同ASGPR之間的受配體結合特性 .

36 、The formation of mixcd ligand complex may either obtained through simultaneous formation, stepwice formation or reproportionation.───它的形成可以是一步同時(shí)生成或逐步生成,也可以是由單一型絡(luò )合物混合生成。

37 、Sequence differences in the ligand binding domain of PXR serve as the molecular basis for the species difference in CYP3A induction.───化學(xué)物通過(guò)PXR調節CYP3A的表達可能是影響化學(xué)物體內代謝的一條重要途徑。

38 、Using hydrophilic ligand [3H]NMS and lipophilic ligand [3H]QNB, two stages of response of mAChR in CCL137 cells to the prolonged treatment with carbachol (GCh) have been demonstrated.───使用親水性配基[~3H]NMS和親脂性、膜通透性配基[~3H]QNB,證實(shí)氨甲酰膽堿(CCh)所致CCL137細胞中mAChR的減少,可分為兩個(gè)不同的階段。

39 、Pressure Effects on Ligand Binding Kinetics for Hemoproteins.───壓力對血紅素蛋白配合基鍵聯(lián)動(dòng)力學(xué)的影響。

40 、ALCAM belongs to immunoglobulin gene superfamily.It is mainly expressed on leucocyte and thymic epithelial cell and is the ligand of CD6 lymphocyte antigen.───ALCAM主要表達在白細胞和胸腺上皮細胞,屬于免疫球蛋白基因超家族的成員,是淋巴細胞抗原CD6的配基。

41 、The effects of tridentate ligand structure, central atom, co-catalyst and supported on property of catalysts are presented.───摘要介紹了三齒配體結構、中心金屬原子、助催化劑、負載化等對催化劑性能的影響；

42 、Probably the new nuclear receptor ligands such as FXR ligand will be the next compound.───新的核受體配體很可能成為下一代化合物，如FXR配體。

43 、Typical examples are oxalate and ethylenediamine as bidentate ligands, citrate as a tridentate ligand, and ethylenediamine tetraacetate (EDTA) as a hexadentate ligand.───典型的例子是草酸和乙二胺為雙齒配體，檸檬酸作為一個(gè)三齒配體，和乙二胺四乙酸（EDTA）作為六齒配體。

44 、Receptor and ligand are transported elsewhere.───受體和配基在別處被傳遞。

45 、When GABA (the ligand) binds to the receptor, the receptor changes its conformation, temporarily opening a channel that admits negatively charged ions into the cell.───當GABA（配位子）與這類(lèi)受體結合時(shí)，受體的構形會(huì )發(fā)生變化，而將通道短暫開(kāi)啟，讓帶負電的氯離子進(jìn)入細胞內。

46 、Adhesive molecule,MHC molecule,Fas and Fas ligand expression were found to be increased in sympathetic ophthalmia eyes.───另外 ,局部還存在黏附分子、MHC和fasL等免疫相關(guān)分子的表達增加。

47 、The effects of tridentate ligand structure, central atom, co catalyst and supported on property of catalysts are presented.───介紹了三齒配體結構、中心金屬原子、助催化劑、負載化等對催化劑性能的影響;

48 、In recent years,T cell,its subsets and costimulator may play important role in the process of SLE.The structure of CD137,its ligand,its function in SLE are reviewed.───本文就共刺激分子CD137的結構、配體、生物學(xué)功能及其在系統性**發(fā)生、發(fā)展中的作用作一綜述。

49 、It is occasionally necessary to use a number system to designate the position of each ligand.───有時(shí)需要用一種編號系統來(lái)標明各配體的位置。

50 、BAFF and APRIL are two novel related members of the TNF ligand superfamily.───BAFF和APRIL是新近發(fā)現的TNF配體超家族2個(gè)關(guān)系密切的成員。

51 、The phenyl substitutents on the cyclopentadienyl ligand affect catalytic activity, stereoregularity , melting temperature of the polystyrene obtained .───在第三章中，這些新型的茂鈦化合物經(jīng)甲基鋁氧烷活化后，催化了苯乙烯聚合。

52 、This paper reviews the application of mixed ligand complex, surfactant and ternary heteropoly acid in polarographic analysis.───本文綜述了混配絡(luò )合物、面活性劑、元雜多酸在極譜分析中的應用,揭示了三元絡(luò )合物在極譜分析中應用的樂(lè )觀(guān)前景。

53 、Some albumin molecules may hae undergone steric modification or ligand binding such that the immunoreactie sites hae become obscured.───某些白蛋白分子也許經(jīng)歷了空間修飾或配體結合上的改變以至于其免疫反應位點(diǎn)被湮沒(méi)。

54 、The chloride ligand trans to the coordinated ethylene is displaced by an entering water molecule.───反向配位的乙烯氯離子配體被一個(gè)進(jìn)入的水分子取代。

55 、The mRNA and protein expression levels of TF in PPAR ligand treaed cells pretreated with LPS were obviously lower than those of the LPS-only group.───PPAR配體處理組中THP-1細胞TF mRNA水平以及蛋白表達量均較單純LPS刺激組明顯降低。

56 、Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) superfamily.───TRAIL是腫瘤壞死因子超家族成員,廣泛表達于多種組織細胞。

57 、The interaction mechanism between ligand and acceptor was revealed in structure.It provides scientific basis for designing higher active compounds.───提出了設計高活性化合物的可能結構要求，并將研究結果用于實(shí)際化合物的設計中，取得了初步結果。

58 、Pharmacophore hypothesis(PH) is fundamental to de novo design of peptide ligand based on the structure of target protein.───在基于靶蛋白結構的多肽分子設計中，藥效假說(shuō)是從頭設計方法的基本前提。

59 、The results indi-cate that increase of basicity and steric hindrance of ligand,and selectingsuitable transitional metal may increase selectivity and activity of polymericcatalysts.───實(shí)驗結果說(shuō)明,增加配位體的堿性和位阻; 選擇合適的過(guò)渡金屬都能提高催化劑的選擇性.

60 、Therefore the separation of amines by the ligand adsorption resin can be achieved from nonaqueous media, which can overcome the leaka...───因此,磺酸銅型樹(shù)脂有望應用于在非水體系中吸附分離或去除某些難溶于水的天然產(chǎn)物如生物堿等物質(zhì)。

61 、To select peptides that bind lipid A from a phage-displayed peptide library.Peptides were screened from a phage-displayed peptide dodecamer library by using lipid A as a ligand.───以脂質(zhì)A為靶標,篩選噬菌體展示十二肽庫,三輪后隨機挑取14個(gè)噬菌體克隆進(jìn)行結合活性鑒定,并對5個(gè)克隆進(jìn)行序列分析。

62 、Our results indicated that small G-protein Rac1 could medicate ligand induced WPB release in HAEC, and the signal pathway of WPB release might be Rac1-dependent ROS regulating mechanism.───小G蛋白Rac1介導HAEC凝血酶誘導的WPB的釋放。 WPB的釋放機制是Rac1依賴(lài)的ROS調節過(guò)程。

63 、Asialofetuin (ASF) is the ligand of ASGP receptor residing on liver cell surface, can bind its receptor specifically and be degradateded by liver cell.───去唾液酸胎球蛋白(ASF)是肝細胞ASGP受體的天然配體，能被ASGP受體特異結合并被肝細胞清除，被廣泛用于肝臟ASGPR研究。

64 、Whether PPARgamma ligand effects on plasma angiotensin II concentration and regular the mRNA expression of ATI-receptor.───明確即AR galnlna配體是否影響外周血漿Angiotensin一n濃度和腎動(dòng)脈ATlmRNA表達。 實(shí)驗材料和方法一建立糖尿病動(dòng)物模型

65 、In the model calculations, we optimized molecular geometry of the parent calixarene ligand 1 and its complex with H3O+.───在這計算模型里，我們得出杯芳烴配合體1和聯(lián)合體H3O+最可能的分子幾何結構。

66 、The glucocorticoid receptor (GR) in peripheral leukocytes of adult and aged athletes was measured by radio-ligandbinding assay using [3H]dexamethasone (Dex) as the ligand.───本文以[~3H]地塞米松(Dex)為配體,用放射配體結合測定法研究了成年運動(dòng)員和老年運動(dòng)員外周血白細胞糖皮質(zhì)激素受體(GR)的變化。

67 、The inducible costimulator (ICOS) and its ligand GL50 are a couple of the newest member of the CD28/B7 family involved in regulating T cell activation.───ICOS及其配體GL50是最近發(fā)現的CD28/B7家族的一對新成員。

68 、The AR protein is composed of four domains,the N-terminal domain(NTD)or transactivation domain,the DNA binding domain(DBD),the flexible hinge region and the ligand binding domain(LBD).───AR的配體,雄激素是主要的內源性性類(lèi)固醇激素,而更多的研究卻表明雄激素在魚(yú)類(lèi)性分化過(guò)程中不起作用,AR在此過(guò)程中的作用尚不清楚。

69 、Methods 410 consecutive sera,sent for routine ANCA testing from hospitalized patients were screened in an anti-BPI ELISA using lightly purified BPI as solid-phrase ligand.───方法應用純化的BPI抗原,以酶聯(lián)免疫吸附方法(ELISA)檢測410份病人血清抗BPI抗體,免疫印跡法驗證部分**血清,分析臨床資料。結果47例抗BPI**。

70 、SAA ligand Lh could induce asymmetric addition of terminal alkyne to aldehydes without using air-sensitive Ti(O~iPr)4and expensive Zn(OTf)2.with good result of high yield (up to 99%) and good enantioselectivities (up to 84%ee).───將SAA配體Lh應用于在無(wú)Ti(O~iPr)_4和Zn(OTf)_2的條件下促進(jìn)端基炔對醛的不對稱(chēng)加成反應中,反應的收率普遍較高,最高達99%,對映體選擇性高達84%ee。

71 、The aim of this article is to review recent devel-opment of CCR7,a newly identified chemokine receptor,and its ligand CCL21and CCL19.───全文就新近發(fā)現的趨化因子受體CCR7及其配體CCL21和CCL19的研究進(jìn)展作一綜述。

72 、TRAIL(TNF-related apoptosis-inducing ligand), identified by Wiley and his colleagues in 1995, is a new member of TNF family.───TRAIL是TNF家族的新成員，其基因是Wiley等于1995年發(fā)現的。

73 、Taurine is noted for its physiological and pharmacological actions;however the reports about taurine as a kind of ligand with cation forming complexes are scarce.───摘要?；撬峋哂袕V泛的生理藥理作用，但是它作為一種配體與陽(yáng)離子進(jìn)行配位的報道卻很少。

74 、Methods: The recombinant aden-ovirus vector carrying murine FLT3 ligand (AdmFL) was constructed, AdmFL and/or ADM were injected into the tumor-bearing mice.───方法:構建攜帶鼠FL的重組腺病毒載體(AdmFL),單獨用其或ADM以及兩者聯(lián)用對實(shí)驗性肝癌小鼠進(jìn)行治療,觀(guān)察抗腫瘤效果。

75 、We need to further validate the relationship between the newly discovered cholesterol sites and the ligand binding sites on these receptors.───我們需要進(jìn)一步地確認在這些受體中新發(fā)現的膽固醇位點(diǎn)和配體位點(diǎn)的關(guān)系?！?/p>

76 、On one hand, complexes 34-43 are a series of complexes of different dimensions based on L1 ligand.───一方面，配合物34-43是由L1構筑的一系列具有不同維度的配合物。

77 、Qing-chuan Zhen, Ze-sheng Li, Jing-fa Xiao, et al, Homology modeling and PAPS ligand (cofactor) binding study of bovine phenol sulfotransferase. J. Mol. Model. 11 , 97, (2005).───張媛,李澤生,肖景發(fā),孫苗等，乙型肝炎表面抗原片段三維結構的同源模建及其配體的設計，高等學(xué)?；瘜W(xué)學(xué)報.26,102,(2005).

78 、The Fas/Fas ligand (FasL) system plays an important role in the transduction of apoptotic signal into the cells.───Fas抗原(APO-1/CD95)與Fas配體(FasL)組成的Fas系統，在將凋亡信號轉導入細胞內發(fā)揮重要作用。

79 、METHODS: Guinea pig lung membrane was used as experimental materials, 3H LTC 4 as radio ligand, FPL 55712 as positive control drug and Gn 3 as test drug.───方法:以豚鼠肺膜為實(shí)驗材料,采用3HLTC4為放射配體,以FPL55712作**對照藥物,Gn3為實(shí)驗藥物,進(jìn)行藥物競爭結合實(shí)驗。

80 、Ligand 3b gave higher enantioselectivity (up to 96% ee) and chemical yield.───在配體3b催化的苯乙炔對醛的不對稱(chēng)加成反應中,產(chǎn)物的ee達到96%。

執行python腳本時(shí)，返回：AttributeError是什么原因？

原因在于： 肯定是在調用此處函數之前，所傳遞進(jìn)來(lái)的變量，此處的self，由于某種原因，沒(méi)有獲得對應的值，而是空值，所以才出現這樣的錯誤。

解決辦法： 自己去一點(diǎn)點(diǎn)反向追蹤，找到具體是哪里，沒(méi)有獲得對應的值。然后再具體情況具體解決。具體如下： 電腦常見(jiàn)問(wèn)題解決

1、無(wú)法自動(dòng)識別硬盤(pán)控制器 使用非正版的個(gè)別操作系統光盤(pán)，在安裝系統時(shí)，容易出現此錯誤。原因是非正版光盤(pán)自動(dòng)加載的硬盤(pán)控制器驅動(dòng)不符合電腦自身需要的驅動(dòng)。這種情況就建議換正版光盤(pán)安裝操作系統。

2、手動(dòng)更新錯誤的驅動(dòng)程序 windows操作系統正常使用，但手動(dòng)更新驅動(dòng)程序把硬盤(pán)控制器的驅動(dòng)程序更新錯誤，導致此故障。解決方法是進(jìn)入windows系統高級菜單，選擇最后一次的正常配置，即可正常進(jìn)入系統。

3、bios設置變化后所導致 windows操作系統正常，但是由于某些原因，用戶(hù)修改了bios設置，導致0x0000007b故障。

gly是二齒配體嗎？

gly是二齒配體

配體（ligand，也稱(chēng)為配基）是一個(gè)化學(xué)名詞，表示可和中心原子（金屬或類(lèi)金屬）產(chǎn)生鍵結的原子、分子和離子。一般而言，配體在參與鍵結時(shí)至少會(huì )提供一個(gè)電子。配體扮演路易斯堿的角色。但在少數情況中配體接受電子，充當路易斯酸。