?chloroquine

chloroquine發(fā)音

英：['kl?:r?kwi:n]　　美：['klo?r??kwa?n]

英：　　美：

chloroquine中文意思翻譯

n. 氯奎(瘧疾的特效藥之一種)

chloroquine常見(jiàn)例句

1 、Chloroquine measurement───氯喹測量

2 、chloroquine phosphate injection───**酸氯喹注射液

3 、chloroquine and primaquine───氯喹及伯氨喹啉

4 、The dosage of chloroquine (CQ)required to inhibit 50% spermidine (SPD) levels in mice RBC infected with CQ-resistant (CR) and sensitive (CS) strains of P. berfjhei were found to be 400mg/kg and 20mg/kg respectively.───抑制伯氏瘧原蟲(chóng)感染RBC中50%精脒量,抗氯喹株需要喂服400mg/kg氯喹,而敏感的為20mg/kg,相差至少20倍。

5 、At present, drugs of curing malaria are: chloroquine, ethylamine pyrimidine et al, but the most serious question is anti-drug character of plasmodia on those drugs, particular to chloroquine.───目前,在臨床上瘧原蟲(chóng)對治療瘧疾的藥物(如氯奎等)有較強的耐藥性,并表現出明顯的交叉耐藥性。

6 、"Chloroquine is sometimes used to treat autoimmune conditions like lupus and arthritis.───“氯喹有時(shí)候能夠用于治療自身免疫性疾病如狼瘡和關(guān)節炎。

7 、Keywords Complex naphthoquine;Chloroquine;Plasmodium vivax malaria;───關(guān)鍵詞復方萘酚喹;氯喹;間日瘧;

8 、chloroquine phosphate syrup───**酸氯喹糖漿

9 、Effects of intravitreous injection of chloroquine on ERG and ultrastructural changes in rabbits───玻璃體內注射氯喹對兔視網(wǎng)膜電圖和超微結構的影響

10 、Wait like chloroquine, Terramycin, digoxin again, in inject place medicaments of extremely easy separate out crystallizes, absorb hard, form bump.───又如氯喹、土霉素、地高辛等，在注射部位極易析出藥物結晶，難以吸收，形成腫塊。

11 、Keywords Phosphatic chloroquine;Jiaweisinisan;Chronic Brucellosis;Ache from bone arthrosis;───**酸氯喹;加味四逆散;慢性布魯氏菌病;骨關(guān)節疼痛;

12 、Keywords Plasmodium berghei;benflumetol;chloroquine;gene expression;drug resistance;───瘧原蟲(chóng);伯氏;本芴醇;氯喹;基因表達;抗藥性;

13 、Nowadays, chloroquine and Atabrine are used to prevent malaria.───如今,氯喹和瘧滌平都被用來(lái)防止瘧疾。

14 、The immunosuppressors are corticosteriod and chloroquine.───免疫抑制劑選用的是強的松和氯喹。

15 、In this thesis, a polarographic reduction wave and two polarographic catalytic waves of chloroquine phosphate in the presence of oxidants such as K2S2Og and H2O, were first studied.───本論文的主要工作是首次研究了抗虐藥物**酸氯喹的極譜還原波和**酸氯喹在過(guò)硫酸鉀和過(guò)氧化氫存在下產(chǎn)生的兩種極譜催化波，探討了**酸氯喹還原波和催化波的機理。

16 、The compond compound seems to boost the effectiveness of several drugs that fight malaria, including chloroquine artemisininand artemisin.───瘧疾寄生蟲(chóng)會(huì )通過(guò)侵入紅細胞來(lái)引發(fā)疾病，因為它們在那里可以通過(guò)含氧蛋白質(zhì)，也就是血色素來(lái)生存。

17 、Abstract.Objective: To detect the risk factors for treatment failure of chloroquine against falciparum malaria in the border area in Yunnan, China.───摘要： 目的 尋找在中國云南省邊境地區氯喹治療惡性瘧失敗的高危因素。

18 、Determination of Chloroquine Phosphate Using its Polarographic Catalytic Wave───極譜催化波法測定**酸氯喹

19 、The compound seems to boost the effectiveness of several drugs that fight malaria, including chloroquine , artemisininand artemisin.───看起來(lái)，它增強了一些抗瘧疾藥的效能，包括氯奎和蒿素。

20 、Safety of chloroquine phosphate in the treatment of systemic lupus erythematosus and rheumatoid arthritis───**酸氯喹在風(fēng)濕病治療中的安全性

21 、Presence of doxycycline and chloroquine means he got a series of shots in the past 72 hours.─── 多四環(huán)素和氯喹存在 說(shuō)明過(guò)去的72小時(shí)他注射了很多次

22 、Keywords chloroquinoline sulfate;base chloroquine;solvent;recrystallization;───硫酸氯喹;鹽基;溶劑;重結晶;

23 、And I can probably get a month supply of the new chloroquine.─── 還可能換來(lái)一整月的新型氯喹[瘧疾特效藥]

24 、Keywords Plasmodium berghei;chloroquine;elimination;monocyte macrophages;crisis form;───關(guān)鍵詞瘧原蟲(chóng);伯氏;氯喹;清除;單核-巨噬細胞;危機狀態(tài);

25 、chloroquine phosphate───**酸氯喹氯喹**酸鹽

26 、Chloroquine, and other basic drugs and dyes are accumulated very considerably.───氯奎、其它堿性藥劑以及染料，積聚得相當多。

27 、Keywords Chloroquine phosphate;Tablets;Polarography;───**酸氯喹;片劑;極譜法;

28 、Keywords chloroquine;hydroxychloroquine;adverse effect;───氯喹;羥基氯喹;藥物不良反應;

29 、For years, the drugs chloroquine and quinine have been frontline treatments for malaria.───多年來(lái)，氯喹和奎寧一直是治療瘧疾的主要藥品。

30 、But the malaria paresite parasite has become resistent resistant to chloroquine quinine, and quinine.───但是瘧疾的寄生蟲(chóng)已經(jīng)能抵抗氯奎寧和奎寧的作用。

31 、This study indicated that artemether was suitable to treat patients withfalciparum malaria either sensitive or resistant to chloroquine in Somalia, Africa.───本研究結果為蒿甲醚用于非洲當地及外來(lái)人群惡性瘧疾病人的治療提供了臨床藥效資料。

32 、Keywords Chloroquine Type 2 diabetes mellitus Insulinase Insulin resistance;───氯喹;2型糖尿病;胰島素酶;胰島素抵抗;

33 、6.In conclusion, detections of alloantibodies by chloroquine elution test and ether elution test were very important for transfusion safety in therapy of patients with AIHA.───結論 :采用氯奎放散試驗、乙醚放散試驗等檢測被自身抗體掩蓋的同種抗體 ,對AIHA患者的安全輸血很重要。

34 、The molecular marker of chloroquine-resistant falciparum malaria subsequently declined in prealence and was undetectable by 2001, suggesting that chloroquine might once again be effectie in Malawi.───對氯喹有抗藥性的惡性瘧的分子特點(diǎn)在隨后的流行中衰落下來(lái)，到2001年幾乎消失，這說(shuō)明在馬拉威氯喹可以重新有效。

35 、Well No.1 was control.Well No.2 contained artemether,pyronaridine and chloroquine concentration of 1.25,0.25 and 1 pmol,respectively.The concentration in well No.3-9 was doubled in order.───實(shí)用寄生蟲(chóng)病雜志1999年第1期第7卷實(shí)驗研究作者：楊品芳楊恒林楊滄江單位：云南省瘧疾防治研究所思茅665000關(guān)鍵詞：惡性瘧原蟲(chóng)；蒿甲醚；咯萘啶；氯喹；體外敏感性測定...

36 、Chloroquine resistance───氯喹抗性

37 、EFFECT OF LOCAL HORMONE INJECTION PLUS LOW DOSES OF CHLOROQUINE PO ON ORAL EROSION LICHEN PLANUS───局部激素注射加小劑量氯喹口服治療糜爛型口腔扁平苔蘚的療效觀(guān)察

38 、Assessment of Therapeutic Efficacy of Chloroquine Against Falciparum Malaria in an Outbreak Area in Xishuangbanna, Yunnan───云南省西雙版納惡性瘧爆發(fā)區氯喹的療效評價(jià)

39 、Keywords Chloroquine;Liver;Reperfusion injury;Respiratory distress syndrome;adult;───氯喹;肝;再灌注損傷;呼吸窘迫綜合征;成人;

40 、Protective effect of chloroquine on endotoxemia mice and its influence on cytokines───氯喹對內毒素血癥小鼠的保護作用以及對細胞因子的影響

41 、Keywords Chloroquine phosphate;Hydrogen peroxide;Parallel catalytic wave of association complex;───**酸氯喹;過(guò)氧化氫;締合平行催化波;

42 、Resolution results of overlapping CE peaks from mixture of chloroquine phosphate and promethazine hydrochloride───**酸氯喹和鹽酸異丙嗪混合物CE重疊峰的分辨結果

43 、Keywords oral lichen planus;chloroquine;ethyl polyenoate soft capsules;dfficacy;───口腔扁平苔癬;**酸氯喹;多烯酸乙酯膠丸;

44 、chloroquine phosphate poisoning───**酸氯化喹啉中毒

45 、chloroquine hydrochloride───[醫] 鹽酸氯奎

46 、Antimalarial drugs (eg, chloroquine) produce concentrations within WBCs and liver cells thousands of times higher than those in plasma.───抗瘧藥（如氯喹）在白細胞內和肝細胞內的濃度要比血漿中的濃度高出數千倍。

47 、Objective To detect the risk factors for treatment failure of chloroquine against falciparum malaria in the border area in Yunnan, China.───目的尋找在中國云南省邊境地區氯喹治療惡性瘧失敗的高危因素。

48 、In addition, still but as a result of drinkWineOr take drug (like hydroxyl chloroquine) and cause toxic.───此外，還可由于飲酒或服藥(如羥基氯喹)而誘發(fā)中毒。

49 、Travel is a significant factor. Malaria prevention varies by geographic region - ie is chloroquine resistant strain present or absent.───旅行是一個(gè)顯著(zhù)的因素。哺乳動(dòng)物的免疫能力與該種類(lèi)動(dòng)物的地域性有關(guān)，

50 、Phosphatic chloroquine───**酸氯喹

51 、chloroquine mustard───氯喹芥子氣

52 、Methods The blood samples of 23 patients with AIHA were identified by routine typing and typing after chloroquine elution test on DIANA auto instrument. Direct and indirect antiglobulin test were done in the same time.───方法用D IANA全自動(dòng)血型儀對23例AIHA患者進(jìn)行ABO、Rh(D)血型常規定型及氯喹放散實(shí)驗后定型,同時(shí)進(jìn)行直、間接抗人球蛋白試驗。

53 、Keywords Chloroquine phosphate;Compound hypotensor capsules;RP-ion-pair-HPLC;───**酸氯喹;復方降壓膠囊;反相離子對液相色譜法;

54 、At low doses, chloroquine moderated many of the symptoms of metabolic syndrome in seeral mouse models of metabolic syndrome and type 2 diabetes.───低劑量的氯喹即可改善代謝綜合征和2型糖尿病鼠模型中很多代謝綜合征相關(guān)癥狀。

55 、But the malaria parasite has become resistant to chloroquine and quinine.And newer drugs, including artemisinin, are becoming less effective.───但瘧疾寄生蟲(chóng)已經(jīng)開(kāi)始對氯喹和奎寧產(chǎn)生抵抗力，而新型的藥物包括青蒿素等也開(kāi)始失去藥效了。

56 、chloroquine sulfate───硫酸氯喹

57 、Chloroquine Diphosphate───二**酸氯喹, 二**酸氯喹啉, 二**酸氯化喹啉[抗瘧藥]

58 、Nevertheless， chloroquine is still used in the treatment of falciparum malaria in some poor endemic regions due to economic and development reasons.───然而，在一些貧困的瘧疾流行區，氯喹仍被用于治療惡性瘧。

59 、But the malaria parasite has become resistant to the chloroquine and quinine.───但是，瘧疾寄生蟲(chóng)開(kāi)始對氯喹和奎寧有抗藥性了。

60 、AIM: To better understand the differences in haemozoin formation and pathogenicity between chloroquine sensitive(N) and chloroquine resistant(RC) strains of Plasmodium berghei.───目的：研究伯氏瘧原蟲(chóng)氯喹敏感株（N）和抗性株（RC）在瘧色素形成和致病性上的差異。

61 、[Methods] The concentrations of chloroquine in the plasma of normal mice and the mice infected with the N or the RC strains of P. berghei were analyzed by reverse phase HPLC.───[方法 ]應用反相高效液相色譜法分別測定正常小鼠、感染伯氏瘧原蟲(chóng)N株和RC株小鼠血漿中的氯喹濃度 ,采用 **87藥物動(dòng)力學(xué)分析軟件對數據進(jìn)行分析 ,從而獲得有關(guān)藥物動(dòng)力學(xué)參數。

62 、Keywords chloroquine phosphate;related substance;HPLC;determination;───**酸氯喹;有關(guān)物質(zhì);高效液相色譜;測定;

63 、But the malaria parasite has become resistant to chloroquine and quinine, and no .───當一個(gè)人被攜帶瘧疾寄生蟲(chóng)的蚊子叮過(guò)后就會(huì )發(fā)病。

64 、If there is plasmodium in blood, usable chloroquine, avoid uses quinine, attack the medicaments such as impaludism quinoline, uncle ammonia quinoline.───如血液中有瘧原蟲(chóng)，可用氯喹，忌用奎寧、撲瘧喹啉、伯氨喹啉等藥物。

65 、chloroquine poisoning───氯喹中毒

66 、Adverse Effects of Chloroquine and Hydroxychloroquine───氯喹與羥基氯喹的不良反應

67 、Differences in immunity between chloroquine sensitive and chloroquine resistant strain───伯氏瘧原蟲(chóng)氯喹敏感株和抗性株感染的免疫差異

68 、One month after stopping chloroquine, all of the subjects underwent malaria challenge with mosquitos infected with P. falciparum.───停用氯喹后一個(gè)月，所有受試者都接受了感染惡性瘧原蟲(chóng)的蚊子的叮咬。

69 、Keywords oral lichen planus;total glucosides of paeony;chloroquine hydroxide;evaluation system;───口腔扁平苔蘚;白芍總苷;羥基氯喹;療效評價(jià)體系;

70 、THE PROTECTIVE EFFECTS OF CHLOROQUINE PHOSPHATE ON INJURED MYOCARDIAL CELL MEMBRANE───**酸氯喹對心肌細胞膜損傷的保護作用

71 、The influence of some factors including the erythrocyte concentration, the starting rate of parasitemia and the cultivation time on the ire vitro determination of chloroquine sensitivity of Plasmodium falciparum were studied.───本文報告紅細胞濃度、起始原蟲(chóng)感染率以及培養時(shí)間等因素,對體外測定惡性瘧原蟲(chóng)氯喹敏感性的影響。

72 、Endotoxin-induced early acute lung injury in rabbits and the protective effects of chloroquine───內毒素致兔早期急性肺損傷及氯喹的保護性作用

73 、Furthermore, we successfully induced metastatic behaviors of RasV12 cells by blocking the lysosomal degradation pathway with anti-malarial drug chloroquine or monensin.───為了進(jìn)一步探討內吞運輸途徑和腫瘤轉移的關(guān)系，我們分別利用抗虐疾藥物氯喹和莫能菌素阻斷溶酶體的降解功能，成功地在RasV12腫瘤細胞中模擬了腫瘤轉移的表型。

74 、Keywords benflumetol;chloroquine;Plasmodium berghei;drug resistance;verapamil;───本芴醇;氯喹;瘧原蟲(chóng);伯氏;抗藥性;維拉帕米;

75 、Chloroquine,another PLA2 inhibitor or SR27417A,a PAF receptor antagonist,were found without such an effect as p-BPB on neutrophil apoptosis.───但另一種PLA2非特異性抑制劑氯喹和血小板激活因子受體拮抗劑SR27417A則無(wú)上述相同的作用。

76 、chloroquine phosphate tablet───**酸氯喹片

77 、11 Ning Li, Junfeng Song, Maotian Xu.Polarographic study of the associations of midecamycin and chloroquine with hydrogen peroxide.Chemical Research in Chinese Universities.Accepted.───研究了麥迪霉素和雙氧水的締合反應機理，對于消除藥物的副作用有指導作用。

78 、Determination of chloroquine phosphate by single-sweep oscillopolarography───單掃描示波極譜法測定**酸氯喹

79 、Efforts at malaria control in the 1950s and 1960s successfully used the insecticide DDT and the medicine chloroquine to eliminate the disease in many temperate and subtropical regions.───1950及60年代，人們成功以殺蟲(chóng)劑DDT和藥物氯化奎寧控制了瘧疾，許多溫帶及亞熱帶地區的瘧疾都已經(jīng)絕跡。

80 、Keywords Speciflc platelet antibody Chloroquine diphosphate salt LCT;───特異性血小板抗體;**酸氯喹;淋巴細胞毒實(shí)驗;

81 、The But the malaria parasite has become reseased resistant to chloroquine quinine and new a drug quinine.───盡管有藥可治，但寄生菌對這些藥物已經(jīng)有了抗藥性。

82 、The results showed the effect of local injecting triamcinolone-A was better than that of taking chloroquine, and also was better than that of taking triamcinolone-A accompanied of chioroquine.───結果顯示確炎舒松-A或確炎舒松-A加服氯化喹啉的近期療效均優(yōu)于氯化喹啉組。

羥氯喹的基本資料

通用名稱(chēng)：羥氯喹

常用名稱(chēng)：硫酸羥基氯喹 硫酸羥氯喹 硫酸羥氯喹啉 羥基氯奎 羥基氯喹硫酸鹽 羥氯喹啉英語(yǔ)名稱(chēng)：Oxychloroquine Plaquenil Sulfate Quensyl Ercoquin HCQ

HYDROXYCHLOROQUINI SULFAS HYDROXYCHLOROQUINI SULFAS Hydroxychloroquinum 商品名稱(chēng)：Plaquenil

金雞納堿的相關(guān)故事

關(guān)于奎寧有一則流傳很廣的故事說(shuō)，1638年當時(shí)秘魯總督的夫人金瓊（Condessa de Chinchon）染上間日瘧，由統治安地斯地區的西班牙省長(cháng)帶來(lái)了一些金雞納樹(shù)樹(shù)皮磨成的粉。據當地的原住民告訴省長(cháng)，這種樹(shù)皮可以退燒，結果真的有效。后來(lái)女伯爵把這帖藥帶回故鄉西班牙，當時(shí)瘧疾在歐洲大陸肆虐，這種樹(shù)皮粉就成為歐洲人首次能有效治療瘧疾的藥品[1]。但經(jīng)歷史研究發(fā)現，可能根本無(wú)此事，總督夫人沒(méi)得過(guò)瘧疾?？鼘幹委煰懠驳淖钣行У男问奖话l(fā)現于1737年,1820年二位法國化學(xué)家白里悌（Pelletier）與卡芬土（Caventou），從規那(quia)的樹(shù)皮中單離出來(lái)，將之稱(chēng)為奎寧或金雞納霜(quinine)，名稱(chēng)來(lái)自印加土語(yǔ)的樹(shù)名quina-quina。 1850年左右開(kāi)始大規模使用.

1527年出版的《本草綱目》提到的常見(jiàn)野生植物青蒿能“治瘧疾寒熱”。1693年，法國傳教士洪若翰曾用金雞納霜治愈康熙帝的瘧疾。后來(lái)，曹雪芹的祖父曹寅因患瘧，曾向康熙帝索要金雞納霜。蘇州織造李煦上奏云:“寅向臣言，醫生用藥，不能見(jiàn)效，必得主子圣藥救我?！笨滴踔篮筇氐亍百n驛馬星夜趕去”，還一再吩咐“若不是瘧疾，此藥用不得，須要認真，萬(wàn)囑萬(wàn)囑?！痹谒幬镖s到之前，曹寅去世。

二戰期間美國的Sterling Winthrop公司以此為引導，合成了氯奎寧（chloroquine），藥效良好。氯奎寧在戰后成為抗瘧最重要的藥物。