?overexpression

overexpression發(fā)音

英：　　美：

overexpression中文意思翻譯

n. 超表達

overexpression常見(jiàn)例句

1 、STK15 protein overexpression may be a novel marker for diagnosing tumor differentiation of colorectal cancer.───STK15蛋白過(guò)表達程度可望作為判定結腸癌分化程度的新指標。

2 、In EC,COX-2 overexpression was significantly associated with high MVD,and high COX-2 and VEGF expressions had a positive correlation with TNM classification,depth of tumour invasion and lymph node metastasis.───COX-2和VEGF在食管癌組織中出現異常高表達并伴有MVD值增加,而且與腫瘤浸潤深度、淋巴結轉移和TNM分期呈正相關(guān)。

3 、To study the prognostic significance between p53 cDNA mutation measured with RT PCR SSCP and P53 protein overexpression by PAb 1801 monoclonal antibody in 100 cases of colorectal adenocarcinomas.───100份大腸癌組織，用RT－PCR－SSCP檢測p53基因cDNA突變；

4 、It is indicated that the expression of E2F1 is increased in the hypertrophic scar and keloid. E2F1 overexpression may play an important role in the proleferation of fibroblasts and in the development of pathological scar.───E2F1基因在病理性瘢痕組織中增高,促進(jìn)瘢痕組織中修復效應細胞的增生,對病理性瘢痕的形成可能起著(zhù)重要作用。

5 、Genetic Improvement of Rice for Disease Resistance and Salt Tolerance by Overexpression of OsiWRKY and OPBP1, Two Different Transcription Factors───利用轉錄因子OsiWRKY和OPBP1基因提高水稻抗病及耐鹽性研究

6 、Overexpression of CD_(44)v6,MMP-9Accelerate the Invasion and Metastasis of Gastric Cancer───CD_(44)v6、MMP-9過(guò)表達促進(jìn)胃癌浸潤轉移

7 、Overexpression of 2 proteins was inhibited significantly during DEN induced hepatcacinogenesis and Brd U LI was reduced strikingly in later stage of model by 981208 agent.───9812 0 8沖劑可明顯抑制誘癌過(guò)程中兩蛋白的**表達 ,顯著(zhù)降低誘癌后期Brd- U細胞標記指數。

8 、Overexpression of p27~(KIP1) induced by Bak gene leads to the arrest in G_1 phase of HCC-9204 cell line───Bak基因誘導P27~(KIP1)基因的過(guò)表達使HCC-9204細胞在G_1期停滯

9 、Effects of bax overexpression on expression of bak and bcl-xl in cultured human RPE cells───Bax過(guò)表達對培養人視網(wǎng)膜色素上皮細胞bak和bcl-xl表達的影響

10 、The overexpression of ILK and MMP-9 genes may play an important role in the oncogenesis and development of NSCLC respectively.───ILK和MMP-9蛋白過(guò)度表達可能分別在NSCLC的發(fā)生和發(fā)展過(guò)程中起重要作用。

11 、Overexpression of P53 Protein in Primary Cholecystic Carcinoma amd Its Clinical Value───原發(fā)性膽囊癌P53過(guò)度表達及臨床意義

12 、The Effect of cdk-5 Overexpression on Neurofilament Phosphorylation───cdk-5過(guò)度表達對神經(jīng)細絲**酸化的影響

13 、P53 is an important tumor suppressor. Abnormal structure and overexpression of C-met and mutation of P53 areclosed associated with the genesis and development of many humancarcinomas.───P53 是重要的腫瘤抑制基因,C-met 基因表達與結構的異常及 P53 基因的突變和多種人類(lèi)腫瘤的發(fā)生、發(fā)展密切相關(guān)。

14 、Chromosomally mediated multidrug resistance in Salmonella typhimurium is generally attributed to the overexpression of the acrAB locus and the mutation in topoisomerase genes.───AcrAB外流泵系統的過(guò)度表達和拓撲異構酶基因突變是導致鼠傷寒沙門(mén)菌產(chǎn)生多重耐藥性 (MAR)的重要原因。

15 、Tumor growth can be promoted by PDGF via autocrine stimulation of malignant cells, overexpression or overactivation of PDGFRs, or stimulation of angiogenesis within the tumor.───PDGF在腫瘤中的自分泌刺激、PDGFR的過(guò)表達或過(guò)度活化或者刺激腫瘤內血管生成都會(huì )促進(jìn)腫瘤生長(cháng)；

16 、A 10 MOI of recombinant nonreplicating adenovirus was found to infect more than 90% of HOS cells within 24 hours by EGFP fluorescence, in which the MPG overexpression and MPG enzyme activity were also detected.───10個(gè)感染增殖指數(MOI)的Ad5HA-MPG可使90%以上HOS感染,感染細胞高表達MPG并具有MPG酶活性。

17 、The overexpression of CD44V6 and Bcl-2 may be l inked to the pathogenesis, development and metastasis of cervical carcinoma. Det ermination of CD44V6 and Bcl-2 may be useful for properly estimating the progno sis of cervical carcinoma.───CD44V6、Bcl 2表達與宮頸癌的發(fā)生 ,發(fā)展及轉移密切相關(guān) ,可作為預測宮頸癌預后的輔助指標

18 、EFFECT OF CDK-5 OVEREXPRESSION ON TAU PHOSPHORYLATION───Cdk-5過(guò)度表達對Tau蛋白**酸化的影響

19 、Cloning and Overexpression of Prokaryotic Ribonucleic acid enzyme HII in Escherichia coli───原核生物核糖核酸酶HII基因的克隆及在大腸桿菌中的高效表達

20 、In two kidney-one clip hypertensive rats, overexpression of ERK-2 and activated c-jun were associated with the VSMC proliferation in renal arteries.───兩腎一夾型高血壓時(shí) ,可出現ERK 2過(guò)表達 ,轉錄相關(guān)基因c jun活化 ,最終使VSMC增多。

21 、Low-expression of PTEN protein may stimulate overexpression of PI3K protein.───PTEN表達的缺失可能刺激了PI3K蛋白的強**表達。

22 、Most of its manifestations are associated with the overexpression of abnormal immunoglobulin in blood and infiltrative destruction of bone.───其皮膚表現可以分成特異性和非特異性。

23 、When overexpressed of QM, alkalinephosphatase activity and nodule mineralization were both increased in MC3T3-E1from QM overexpression cultures relative to normal expression QM cultures.───為了進(jìn)一步研究QM基因在成骨細胞骨質(zhì)形成和代謝中的作用,我們構建了真核表達載體pcDNA3.1/myc-His A/QM并轉染到MC3T3-E1中建立過(guò)表達QM蛋白的細胞系,研究其表達上調后對細胞的影響。

24 、It is also concluded that human ASPM overexpression is a useful predictive factor for early tumor recurrence after tumor resection, and a prognostic factor associated with poor prognosis.───另外，我們也認為人類(lèi)ASPM基因的過(guò)量表現可以作為一個(gè)有效的手術(shù)后腫瘤早期再發(fā)及預后較差的預測因子。

25 、ASPM overexpression plays important role in the tumor cell proliferation, differentiation, and invasion/metastasis, probably via the downregulation of p27 and upregulation of stathmin.───ASPM基因的過(guò)量表現在腫瘤的細胞增殖、細胞分化以及腫瘤侵犯與轉移扮演著(zhù)重要的角色。

26 、Overexpression of JUN after global cerebral ischemia/reperfusion participates in the neural injury procedure and heat shock precondition performes its brain protective function through its suppressive effect on the overexpression of c-jun.───全腦缺血再灌注損傷后JUN蛋白過(guò)度表達參與了神經(jīng)元損傷過(guò)程,熱休克預處理通過(guò)下調JUN蛋白過(guò)度表達具有腦保護作用。

27 、The predictor value of HER2/neu overexpression in breast cancer patients with undergoing surgery and CMF adjuvant therapy───HER2/neu表達對乳腺癌術(shù)后應用CMF化療病人預后的影響

28 、Our findings, for the first time, revealed a new biological activity for eIF5A as the regulator of p53. Overexpression of eIF5A or its EFP domain resulted in up-regulation of p53, and silencing eIF5A by siRNA reduced p53 protein level.───eIF5A過(guò)表達能導致p53蛋白上調,而eIF5A siRNA則通過(guò)抑制內源性eIF5A的表達而下調p53蛋白水平。

29 、Keywords human endostatin;DNA recombination;gene overexpression;───人內皮生長(cháng)抑素;DNA重組;基因高效表達;

30 、THE RELATIONSHIPS BETWEEN OVEREXPRESSION OF p53 BOTH AND ESOPHAGEAL CANCER(EC) AND THE RISK FACTORS OF EC IN LIN COUNTY───p53高表達與林縣食管癌及其危險因素關(guān)系的分子流行病學(xué)研究

31 、Overexpression of AK fbr gene in C.───AKfbr基因在C.

32 、Hur K,Gazdar AF,Rathi A,et al. Overexpression of human telomerase RNA in Helicobacter pylori-infected human gastric mucosa[J]. Cancer Res, 2000,91 ( 11 ): 1148.───司君利,劉吉勇,元玉琴.幽門(mén)螺桿菌感染與胃粘膜端粒酶活性關(guān)系的研究[J].世界華人消化雜志,1999,7(5):429.

33 、Keywords periodontitis;osteoprotegerin;OPG;RANKL;alveolar bone overexpression;gene therapy;───關(guān)鍵詞牙周炎;骨保護素;OPG;RANKL;骨吸收;基因治療;

34 、Conclusion: The present study demonstrated HDGF overexpression is correlated with tumor grades, recurrence, proliferation, and tumor immunity in breast cancer.───中文摘要目的:HDGF是一個(gè)特殊的生長(cháng)因子,HDGF在各種癌癥的發(fā)病過(guò)程和預后扮演重要的角色,例如肝癌,胃癌和非小細胞肺癌。

35 、ADRB2 inhibition confers cell invasion and transforms benign prostate epithelial cells, whereas ADRB2 overexpression counteracts EZH2-mediated oncogenesis.───ADRB2受到抑制后促進(jìn)腫瘤細胞的侵襲和良性的前列腺上皮細胞的轉化，因此ADRB2過(guò)表達干擾了EZH2調節的腫瘤生成。

36 、The overexpression of COX-2,cyclinD1 in PA and CPA was positively correlated with tumor recurrence and malignant transformation,they probably play an important role in the occurrence and development of CPA in the parotid gland.───COX-2、cyclinD1在PA、CPA中的過(guò)表達與腫瘤的復發(fā)、惡變有明顯關(guān)系,二者在PA、CPA的發(fā)生發(fā)展中可能具有一定的作用。

37 、NFI-A overexpression decreased osteoclast formation and function with down-regulation of M-CSFR levels.───NFI-A的過(guò)表達降低破骨細胞的形成，比并抑制其功能，同時(shí)伴隨著(zhù)M-CSFR水平的下調。

38 、1) There is overexpression of COX-2 in PC-3m cell line as in PC-3 cell line.───l）同 PC上細胞系一樣，PC上m細胞系中存在 COX1 mRNA及蛋白質(zhì)表達。

39 、The effect of overexpression of Hira on embryogenesis of Drosophila melanogaster───Hira基因的過(guò)量表達對果蠅早期胚胎發(fā)育的影響

40 、DNR induced overexpression of Pgp in K562/D cells;───DNR誘導了 K5 6 2 / D細胞的 Pgp過(guò)度表達。

41 、The loss of PTEN expression is closely related to tumorigenesis and development of the UEC, and the overexpression of p53 gene is related to tumorigenesis and development of the USC.───PTEN突變和表達缺失與宮內膜樣癌的發(fā)生、發(fā)展有關(guān)。 p53基因突變和過(guò)表達與宮內膜漿液性癌發(fā)生發(fā)展關(guān)系密切。

42 、Positive Relationship of p53 and p21 Overexpression in Lymph Node Metastasis Propensity in Patients with Gastric Cancer───P53和P21過(guò)表達與胃癌淋巴結轉移呈正相關(guān)

43 、The multidrug resistance of K562/D cells can be induced by DNR which is related to the Pgp overexpression, and verapamil reversed the DNR resistance by increasing the intracellular accumulation of DNR.───DNR誘導了 K5 6 2 / D細胞的 Pgp過(guò)度表達 ,異搏定通過(guò)抑制 Pgp功能逆轉了 Pgp介導的K5 6 2 / D細胞的多藥耐藥性

44 、pET30-Cre overexpression vector───pET30-Cre高效表達

45 、Overexpression of Pyst2 mRNA in AML predicts poor chemotherapy response───Pyst2在急性髓系白血病中的表達及其意義

46 、Overexpression of bcl-2 induced by hypoxic preconditioning may play a role in sustaining the stability of MMP.───低氧預處理誘發(fā)bcl-2高表達可能是線(xiàn)粒體膜電位穩定性增強的機制之一。

47 、Like other tumors, development of ovarian cancer was related with the overexpression of oncogenes and the dysfunction of tumor suppressor genes.───卵巢癌的發(fā)生與其他腫瘤一樣,存在癌基因的過(guò)表達與抑癌基因的失活。

48 、CD7+ CD56 + AML might constitute a distinct biologic and clinical disease entity. Our data showed that CD7+CD56+ AML associated with less anemia, overexpression of PgP and CD34 and a high incidence of central nervous system involvement.───CD7+CD56+AML具有獨特的臨床生物學(xué)特征,較少貧血,高表達PgP和CD34,常伴有中樞神經(jīng)系統浸潤。

49 、One of the possible mechanism involved in perinatal of ICP is apoptosis caused by overexpression of bax in syncytiotrophoblast leading placental dysfunction.───ICP患者**合體滋養細胞bax基因過(guò)度表達,**細胞凋亡率升高,影響**功能,可能是ICP并發(fā)圍生兒缺氧的病理生理基礎之一。

50 、5 Tang RF, Itakura J, Aikawa T, Matsuda K, Fujii H, Korc M, Matsumoto Y. Overexpression of lymphangiogenic growth───4李志偉,馮玉泉,顧萬(wàn)清,周寧新,張文智,黃志強.胰頭癌外科療效的臨床分析.中華肝膽外科雜志2006;12:92-94

51 、The Amplication and Overexpression of TRIO and its Correlation with Carcinogenesis and Bladder Cancer Growth───使用組織微陣列對浸潤性膀胱癌癌基因的研究

52 、Effects of Smac Gene Overexpression on Chemotherapeutic Sensitivity of Gastric Cancer Cell Line MKN-45───Smac基因過(guò)表達對胃癌細胞株MKN-45化療敏感性的影響

53 、Atherosclerosis ;Proteins ;overexpress ;Acid lipase ;lysosomal ;───動(dòng)脈粥樣硬化 ;

54 、none - overexpression ErbB2 breast cancer───ErbB2非過(guò)表達乳腺癌

55 、Comparative proteome analysis of AspC gene overexpression in E.coli BL21───AspC基因導入前后E·coli BL21蛋白質(zhì)組的解析

56 、A case control study on relationship between overexpression of P53 protein and esophageal carcinoma in Linxian───P53蛋白高表達與林縣食管癌關(guān)系的病例對照研究

57 、P gp and LRP sometimes had co overexpression in glioma tissues.───P gp和LRP在人腦膠質(zhì)瘤中有共同表達。

58 、The lose of APC or bcl-2 and c-met gene overexpression are contributed to the occurance and development of GC.───APC基因的失活、bcl-2和c-met基因的過(guò)表達對胃癌的發(fā)生、發(fā)展起促進(jìn)作用;

59 、Additionally, ITK was required for efficient HIV transcription, and overexpression of ITK increased both viral transcription and virus-like particle formation.───但由于艾滋病病毒變異速度快，容易對某種特定療法產(chǎn)生抗性，因此迄今沒(méi)有誕生能治愈艾滋病的療法。

60 、Different phenotypes of P68 between tumouric cell li nes (HeLa, TC 3H 10) and non-tumouric cell lines (NIH3T3 and NC 3H 10 ) were observed, and we reasoned that overexpression of P68 might profoundly a ffect cellular growth properties.───以前的工作表明P68核蛋白在同一細胞系不同生長(cháng)階段的表型不同。 它在腫瘤細胞 (HeLa和TC3H10 )與非腫瘤細胞 (NIH3T3和NC3H10 )之間表型亦有明顯差異。

61 、There were no correlation between p-gp and blc-2.Conclusion Overexpression of bcl-2 or p-gp could result in poor prognosis of AL.───P gp和Bcl 2表達無(wú)相關(guān)性。 結論 P gp和Bcl 2高表達均預示AL預后不良。

62 、Uncoupling Protein 4 Overexpression Promotes Proliferation and Inhibits Apoptosis and Differentiation of Preadipocytes [A];───中華醫學(xué)會(huì )第十四次全國兒科學(xué)術(shù)會(huì )議論文匯編 [C];

63 、The overexpression of p53 and bcl 2 proteins may be involved in tumorigenesis and be correlated with the differentiation of NPSC. These will help identify the prognosis of NPSC.───p5 3和bcl 2蛋白均參與鼻咽鱗癌的發(fā)生與分化 ,其表達水平的不同有助于預后判斷 ;

64 、BAFF overexpression or deficiency can destroy B-cell homeostasis and induce autoimmu...───BAFF的缺陷或過(guò)量表達均能引起機體的免疫失衡,從而誘發(fā)多種疾病。

65 、AKT2 overexpression in GA may promote lymph node metastasis and progression of the disease.───AKT2的過(guò)表達可能參與了GA的淋巴結轉移和病程進(jìn)展;

66 、Relation of C erbB2 and Ki 67 overexpression to growth and proliferation of tumor cells in breast cancer───乳腺癌中C-erbB-2和Ki-67過(guò)度表達與癌細胞生長(cháng)、增殖的關(guān)系

67 、Overexpression or functional abnormality of membrane drug transport proteins of ATP-binding cassette(ABC)family which results in an increased drug efflux,could be one of the main mechanisms.───其中,腫瘤細胞膜上ATP結合盒(ABC)轉運蛋白的表達或功能異常是腫瘤細胞產(chǎn)生MDR的重要機制之一。

68 、Overexpression of cyc lin D1 and cdk4 were revealed in these samples and p16 was undertectable.───p16在卵巢癌中低表達 ,cyclinD1和cdk4過(guò)度表達 ;

69 、Overexpression of MUC5AC,MUC5B and MUC2 have been described in asthma secretions,Inflammatory mediators linked to asthma also take part in the regulation of mucus hypersecretion.───哮喘患者分泌的黏液中主要表現為MUC5AC、MUC5B和MUC2的過(guò)度表達,哮喘相關(guān)的炎性介質(zhì)也參與了哮喘黏液高分泌的調控。

70 、Inducible overexpression of Bak sensitizes HCC-9204 cells to apoptosis induced by doxorubicin───可誘導型及Bak基因過(guò)度表達對多柔比星誘導HCC-9204細胞凋亡的增敏作用(英文)

71 、Cyclin E overexpression was associated with the histological type of EC, being more frequent in non-endometrioid endometrial carcinomas (NEECs, 5 out of 5 case) than in ECs (18 out of 38, 47.37%) (P=0.035).───cyclin E蛋白與子宮內膜癌的組織學(xué)類(lèi)型、分級以及肌層浸潤深度顯著(zhù)相關(guān):其在子宮內膜樣癌和非內膜樣癌中**率分別為47.37%和5/5,兩者之間比較差異具有統計學(xué)意義(P

72 、The MPG overexpression HOS cells were significantly more sensitive to the DNA damage agents, including MMS, MNNG, and TMZ, with changes in the IC50 of 6.0, 4.5, and 2.5 fold respectively.───MPG過(guò)表達HOS顯著(zhù)地提高DNA損傷性化療藥物MMS、MNNG和TMZ的敏感性,其半數抑制濃度(IC50)值分別下降了6·0、4·5和2·5倍。

73 、Patients with MMP-9 or TIMP-1 overexpression lived significantly shorter than those have low MMP-9 or TIMP-1 expression.───MMP-9與TIMP-1是NSCLC患者重要的臨床預后判斷指標，低表達者生存期長(cháng)于高表達者；

74 、The sensitivity of AML cells with Pgp overexpression to cytarabine(AraC) and daunorubicin(DNR) was significantly lower than that of AML cells with Pgp lower level expression(P───Pgp高表達的AML細胞對阿糖胞苷(AraC)和柔紅霉素 (DNR)藥物敏感性低于低水平表達者 (P

75 、The incidences of overexpression of p 53 and C erbB 2,C ras,C myc were 56%(14/25),56%(14/25),48%(12/25),48%(12,25),respectively.───25例卵巢粒層細胞瘤中p53、C－erbB2、C－ras、C－myc的過(guò)度表達率分別為56%、56%、48%、48%。

76 、Overexpression of Bak gene may lead to apoptosis in hepatocellular carcinoma───Bak基因過(guò)表達誘導肝癌細胞凋亡

77 、TRAIL combined with Herceptin can effectively inhibit breast cell lines SKBR-3 even these cells are resistant to TRAIL alone,which may be a new therapeutic method for treatment of C-erbB2 overexpression breast cancer.───乳腺癌SKBR-3細胞株對TRAIL不敏感,但TRAIL與Herceptin聯(lián)用可增加抗腫瘤作用,可能成為一種對C-erbB2過(guò)表達乳腺癌的新的治療方法。

78 、However, in HCC with Fas expression, the ratio of apoptosis increased significantly and PCNA-LI remained, it means that the apoptosis could be promoted by the overexpression of Fas.───FaS**HCC細胞凋亡指數顯著(zhù)增高，而PCNA一LI改變不顯著(zhù)，提示Fas蛋白過(guò)度表達可促進(jìn)HCC的細胞凋亡，而對其細胞增殖可能影響不大。

79 、Keywords Cadmium stress;zinc stress;ascorbate peroxidase;gene overexpression;transgenic ric;───關(guān)鍵詞鎘脅迫;鋅脅迫;抗壞血酸過(guò)氧化物酶;基因過(guò)量表達;轉基因水稻;

80 、Overexpression of PML growth suppressor suppresses growth and tumorigenicity of prostatic cancer cells───PML生長(cháng)抑制因子過(guò)表達抑制前列腺癌細胞生長(cháng)和致瘤能力的實(shí)驗研究

在生物實(shí)驗上的分組中kd或ko或oe是什么意思？

oe overexpressionkd knockdowm ko knockout

在生物實(shí)驗上的分組中kd或ko或oe是什么意思？

在生物學(xué)中,kD表示分子量的單位道爾頓,一般寫(xiě)的是Da,kDa就是1000Da;Kd則表示解離平衡常數。